2b2x: Difference between revisions

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[[Image:2b2x.gif|left|200px]]<br /><applet load="2b2x" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2b2x.gif|left|200px]]
caption="2b2x, resolution 2.200&Aring;" />
 
'''VLA1 RdeltaH I-domain complexed with a quadruple mutant of the AQC2 Fab'''<br />
{{Structure
|PDB= 2b2x |SIZE=350|CAPTION= <scene name='initialview01'>2b2x</scene>, resolution 2.200&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene>
|ACTIVITY=
|GENE= Itga1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
}}
 
'''VLA1 RdeltaH I-domain complexed with a quadruple mutant of the AQC2 Fab'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2B2X is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2X OCA].  
2B2X is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B2X OCA].  


==Reference==
==Reference==
Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design., Clark LA, Boriack-Sjodin PA, Eldredge J, Fitch C, Friedman B, Hanf KJ, Jarpe M, Liparoto SF, Li Y, Lugovskoy A, Miller S, Rushe M, Sherman W, Simon K, Van Vlijmen H, Protein Sci. 2006 May;15(5):949-60. Epub 2006 Apr 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16597831 16597831]
Affinity enhancement of an in vivo matured therapeutic antibody using structure-based computational design., Clark LA, Boriack-Sjodin PA, Eldredge J, Fitch C, Friedman B, Hanf KJ, Jarpe M, Liparoto SF, Li Y, Lugovskoy A, Miller S, Rushe M, Sherman W, Simon K, Van Vlijmen H, Protein Sci. 2006 May;15(5):949-60. Epub 2006 Apr 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16597831 16597831]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: computational design]]
[[Category: computational design]]


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