3lpq: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3lpq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LPQ FirstGlance]. <br> | <table><tr><td colspan='2'>[[3lpq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LPQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LPQ FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">C10orf70, CISD1, MDS029, ZCD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">C10orf70, CISD1, MDS029, ZCD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lpq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lpq RCSB], [http://www.ebi.ac.uk/pdbsum/3lpq PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lpq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lpq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lpq RCSB], [http://www.ebi.ac.uk/pdbsum/3lpq PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CISD1_HUMAN CISD1_HUMAN]] Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions.<ref>PMID:17584744</ref> <ref>PMID:17766440</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conformational heterogeneity in the ligand environment.,Conlan AR, Paddock ML, Homer C, Axelrod HL, Cohen AE, Abresch EC, Zuris JA, Nechushtai R, Jennings PA Acta Crystallogr D Biol Crystallogr. 2011 Jun;67(Pt 6):516-23. Epub 2011 May 17. PMID:21636891<ref>PMID:21636891</ref> | Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conformational heterogeneity in the ligand environment.,Conlan AR, Paddock ML, Homer C, Axelrod HL, Cohen AE, Abresch EC, Zuris JA, Nechushtai R, Jennings PA Acta Crystallogr D Biol Crystallogr. 2011 Jun;67(Pt 6):516-23. Epub 2011 May 17. PMID:21636891<ref>PMID:21636891</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
== References == | == References == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Abresch, E C | [[Category: Abresch, E C]] | ||
[[Category: Axelrod, H L | [[Category: Axelrod, H L]] | ||
[[Category: Cohen, A E | [[Category: Cohen, A E]] | ||
[[Category: Conlan, A R | [[Category: Conlan, A R]] | ||
[[Category: Homer, C | [[Category: Homer, C]] | ||
[[Category: Jennings, P A | [[Category: Jennings, P A]] | ||
[[Category: Nechushtai, R | [[Category: Nechushtai, R]] | ||
[[Category: Paddock, M L | [[Category: Paddock, M L]] | ||
[[Category: Zuris, J | [[Category: Zuris, J]] | ||
[[Category: 2fe-2s cluster]] | [[Category: 2fe-2s cluster]] | ||
[[Category: Cdgsh protein fold]] | [[Category: Cdgsh protein fold]] | ||
