1yo7: Difference between revisions
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==Re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle== | |||
<StructureSection load='1yo7' size='340' side='right' caption='[[1yo7]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1yo7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YO7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YO7 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rop|1rop]]</td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rop ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yo7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yo7 RCSB], [http://www.ebi.ac.uk/pdbsum/1yo7 PDBsum]</span></td></tr> | ||
[[1yo7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YO7 OCA]. | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/ROP_ECOLI ROP_ECOLI]] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events. | |||
==See Also== | ==See Also== | ||
*[[Rop protein|Rop protein]] | *[[Rop protein|Rop protein]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Emery, S C | [[Category: Emery, S C]] | ||
[[Category: Sagermann, M | [[Category: Sagermann, M]] | ||
[[Category: Sander, C | [[Category: Sander, C]] | ||
[[Category: Four-helix bundle]] | [[Category: Four-helix bundle]] | ||
[[Category: Protein design]] | [[Category: Protein design]] | ||
[[Category: Re-engineering of topology]] | [[Category: Re-engineering of topology]] | ||
[[Category: Replication regulator]] | [[Category: Replication regulator]] | ||
