2bb7: Difference between revisions

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[[Image:2bb7.gif|left|200px]]<br /><applet load="2bb7" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2bb7.gif|left|200px]]
caption="2bb7, resolution 1.700&Aring;" />
 
'''Mn Form Of E. coli Methionine Aminopeptidase In Complex With a quinolinyl sulfonamide inhibitor'''<br />
{{Structure
|PDB= 2bb7 |SIZE=350|CAPTION= <scene name='initialview01'>2bb7</scene>, resolution 1.700&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=QMS:N-(QUINOLIN-8-YL)METHANESULFONAMIDE'>QMS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18]
|GENE= map ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Mn Form Of E. coli Methionine Aminopeptidase In Complex With a quinolinyl sulfonamide inhibitor'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2BB7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=QMS:'>QMS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Methionyl_aminopeptidase Methionyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.18 3.4.11.18] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BB7 OCA].  
2BB7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BB7 OCA].  


==Reference==
==Reference==
Metal mediated inhibition of methionine aminopeptidase by quinolinyl sulfonamides., Huang M, Xie SX, Ma ZQ, Hanzlik RP, Ye QZ, Biochem Biophys Res Commun. 2006 Jan 13;339(2):506-13. Epub 2005 Nov 15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16300729 16300729]
Metal mediated inhibition of methionine aminopeptidase by quinolinyl sulfonamides., Huang M, Xie SX, Ma ZQ, Hanzlik RP, Ye QZ, Biochem Biophys Res Commun. 2006 Jan 13;339(2):506-13. Epub 2005 Nov 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16300729 16300729]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Methionyl aminopeptidase]]
[[Category: Methionyl aminopeptidase]]
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[[Category: trimetallic]]
[[Category: trimetallic]]


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