2bbq: Difference between revisions

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[[Image:2bbq.jpg|left|200px]]<br /><applet load="2bbq" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2bbq.jpg|left|200px]]
caption="2bbq, resolution 2.3&Aring;" />
 
'''STRUCTURAL BASIS FOR RECOGNITION OF POLYGLUTAMYL FOLATES BY THYMIDYLATE SYNTHASE'''<br />
{{Structure
|PDB= 2bbq |SIZE=350|CAPTION= <scene name='initialview01'>2bbq</scene>, resolution 2.3&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=UMP:2'-DEOXYURIDINE+5'-MONOPHOSPHATE'>UMP</scene> and <scene name='pdbligand=PFG:10-PARPARGYL-5,8-DIDEAZAFOLATE-4-GLUTAMIC ACID'>PFG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45]
|GENE=
}}
 
'''STRUCTURAL BASIS FOR RECOGNITION OF POLYGLUTAMYL FOLATES BY THYMIDYLATE SYNTHASE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2BBQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=UMP:'>UMP</scene> and <scene name='pdbligand=PFG:'>PFG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBQ OCA].  
2BBQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BBQ OCA].  


==Reference==
==Reference==
Structural basis for recognition of polyglutamyl folates by thymidylate synthase., Kamb A, Finer-Moore J, Calvert AH, Stroud RM, Biochemistry. 1992 Oct 20;31(41):9883-90. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1390771 1390771]
Structural basis for recognition of polyglutamyl folates by thymidylate synthase., Kamb A, Finer-Moore J, Calvert AH, Stroud RM, Biochemistry. 1992 Oct 20;31(41):9883-90. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1390771 1390771]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transferase(methyltransferase)]]
[[Category: transferase(methyltransferase)]]


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