2bel: Difference between revisions

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[[Image:2bel.gif|left|200px]]<br /><applet load="2bel" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2bel.gif|left|200px]]
caption="2bel, resolution 2.11&Aring;" />
 
'''STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE'''<br />
{{Structure
|PDB= 2bel |SIZE=350|CAPTION= <scene name='initialview01'>2bel</scene>, resolution 2.11&Aring;
|SITE= <scene name='pdbsite=AC1:Cl+Binding+Site+For+Chain+C'>AC1</scene>
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=CBO:CARBENOXOLONE'>CBO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/11-beta-hydroxysteroid_dehydrogenase 11-beta-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.146 1.1.1.146]
|GENE=
}}
 
'''STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE'''
 


==Disease==
==Disease==
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==About this Structure==
==About this Structure==
2BEL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=NAP:'>NAP</scene> and <scene name='pdbligand=CBO:'>CBO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/11-beta-hydroxysteroid_dehydrogenase 11-beta-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.146 1.1.1.146] Known structural/functional Site: <scene name='pdbsite=AC1:Cl+Binding+Site+For+Chain+C'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BEL OCA].  
2BEL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BEL OCA].  
[[Category: 11-beta-hydroxysteroid dehydrogenase]]
[[Category: 11-beta-hydroxysteroid dehydrogenase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: steroid metabolism]]
[[Category: steroid metabolism]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:37:00 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:00:56 2008''

Revision as of 14:00, 20 March 2008

File:2bel.gif


Drag the structure with the mouse to rotate
2bel, resolution 2.11Å
Sites: AC1
Ligands: CL, NAP and CBO
Activity: 11-beta-hydroxysteroid dehydrogenase, with EC number 1.1.1.146
Coordinates: save as pdb, mmCIF, xml



STRUCTURE OF HUMAN 11-BETA-HYDROXYSTEROID DEHYDROGENASE IN COMPLEX WITH NADP AND CARBENOXOLONE


Disease

Known diseases associated with this structure: Cortisone reductase deficiency OMIM:[600713]

About this Structure

2BEL is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Mar 20 16:00:56 2008

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