3n0u: Difference between revisions
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==Crystal structure of Tm1821, the 8-oxoguanine DNA glycosylase of Thermotoga maritima== | |||
<StructureSection load='3n0u' size='340' side='right' caption='[[3n0u]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3n0u]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N0U FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ogg, Tm1821, TM_1821 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2336 Thermotoga maritima])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n0u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n0u RCSB], [http://www.ebi.ac.uk/pdbsum/3n0u PDBsum]</span></td></tr> | |||
== | </table> | ||
[[3n0u]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N0U OCA]. | == Function == | ||
[[http://www.uniprot.org/uniprot/OGG1_THEMA OGG1_THEMA]] Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites) (By similarity). | |||
==See Also== | ==See Also== | ||
*[[DNA | *[[DNA glycosylase|DNA glycosylase]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Thermotoga maritima]] | [[Category: Thermotoga maritima]] | ||
[[Category: Cooper, D R | [[Category: Cooper, D R]] | ||
[[Category: Derewenda, Z S | [[Category: Derewenda, Z S]] | ||
[[Category: ISFI, Integrated Center for Structure and Function Innovation | [[Category: ISFI, Integrated Center for Structure and Function Innovation]] | ||
[[Category: Roy, A | [[Category: Roy, A]] | ||
[[Category: 8-oxoguanine]] | [[Category: 8-oxoguanine]] | ||
[[Category: Base excision repair]] | [[Category: Base excision repair]] | ||
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[[Category: Isfi]] | [[Category: Isfi]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
[[Category: Protein structure initiative | [[Category: PSI, Protein structure initiative]] | ||
[[Category: Structural genomic]] | [[Category: Structural genomic]] | ||
Revision as of 04:46, 25 December 2014
Crystal structure of Tm1821, the 8-oxoguanine DNA glycosylase of Thermotoga maritima
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