2w7d: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w7d RCSB], [http://www.ebi.ac.uk/pdbsum/2w7d PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w7d RCSB], [http://www.ebi.ac.uk/pdbsum/2w7d PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/Q7SIB6_BACST Q7SIB6_BACST]] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity).[HAMAP-Rule:MF_00051] Interconversion of serine and glycine (By similarity).[RuleBase:RU000585] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
==See Also== | |||
*[[Serine hydroxymethyltransferase|Serine hydroxymethyltransferase]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Geobacillus stearothermophilus]] | [[Category: Geobacillus stearothermophilus]] | ||
[[Category: Glycine hydroxymethyltransferase]] | [[Category: Glycine hydroxymethyltransferase]] | ||
[[Category: Bhavani, B S | [[Category: Bhavani, B S]] | ||
[[Category: Bisht, S | [[Category: Bisht, S]] | ||
[[Category: Kaul, P | [[Category: Kaul, P]] | ||
[[Category: Murthy, M R.N | [[Category: Murthy, M R.N]] | ||
[[Category: Prakash, V | [[Category: Prakash, V]] | ||
[[Category: Rajaram, V | [[Category: Rajaram, V]] | ||
[[Category: Rao, N Appaji | [[Category: Rao, N Appaji]] | ||
[[Category: Savithri, H S | [[Category: Savithri, H S]] | ||
[[Category: One-carbon metabolism]] | [[Category: One-carbon metabolism]] | ||
[[Category: Plp-dependent enzyme]] | [[Category: Plp-dependent enzyme]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||