2ell: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ell]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ELL FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ell]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ELL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ELL FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ANP32B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ANP32B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ell FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ell OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ell RCSB], [http://www.ebi.ac.uk/pdbsum/2ell PDBsum], [http://www.topsan.org/Proteins/RSGI/2ell TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ell FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ell OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ell RCSB], [http://www.ebi.ac.uk/pdbsum/2ell PDBsum], [http://www.topsan.org/Proteins/RSGI/2ell TOPSAN]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/AN32B_HUMAN AN32B_HUMAN]] Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.<ref>PMID:20538007</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Harada, T | [[Category: Harada, T]] | ||
[[Category: Kigawa, T | [[Category: Kigawa, T]] | ||
[[Category: Koshiba, S | [[Category: Koshiba, S]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Tanaka, A | [[Category: Tanaka, A]] | ||
[[Category: Tochio, N | [[Category: Tochio, N]] | ||
[[Category: Umehara, T | [[Category: Umehara, T]] | ||
[[Category: Watanabe, S | [[Category: Watanabe, S]] | ||
[[Category: Yokoyama, S | [[Category: Yokoyama, S]] | ||
[[Category: Acidic protein rich in leucine]] | [[Category: Acidic protein rich in leucine]] | ||
[[Category: Gene regulation]] | [[Category: Gene regulation]] | ||
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[[Category: Nppsfa]] | [[Category: Nppsfa]] | ||
[[Category: Phapi2 protein]] | [[Category: Phapi2 protein]] | ||
[[Category: Rsgi]] | [[Category: Rsgi]] | ||
[[Category: Silver-stainable protein ssp29]] | [[Category: Silver-stainable protein ssp29]] | ||
