2c5a: Difference between revisions

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[[Image:2c5a.gif|left|200px]]<br /><applet load="2c5a" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2c5a.gif|left|200px]]
caption="2c5a, resolution 1.400&Aring;" />
 
'''GDP-MANNOSE-3', 5'-EPIMERASE (ARABIDOPSIS THALIANA), Y174F, WITH GDP-BETA-L-GALACTOSE BOUND IN THE ACTIVE SITE'''<br />
{{Structure
|PDB= 2c5a |SIZE=350|CAPTION= <scene name='initialview01'>2c5a</scene>, resolution 1.400&Aring;
|SITE= <scene name='pdbsite=AC1:Btb+Binding+Site+For+Chain+B'>AC1</scene>
|LIGAND= <scene name='pdbligand=GDC:GUANOSINE-5'-DIPHOSPHATE-BETA-L-GALACTOSE'>GDC</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene> and <scene name='pdbligand=FMT:FORMIC ACID'>FMT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/GDP-mannose_3,5-epimerase GDP-mannose 3,5-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.18 5.1.3.18]
|GENE=
}}
 
'''GDP-MANNOSE-3', 5'-EPIMERASE (ARABIDOPSIS THALIANA), Y174F, WITH GDP-BETA-L-GALACTOSE BOUND IN THE ACTIVE SITE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2C5A is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] with <scene name='pdbligand=GDC:'>GDC</scene>, <scene name='pdbligand=NAD:'>NAD</scene>, <scene name='pdbligand=BTB:'>BTB</scene> and <scene name='pdbligand=FMT:'>FMT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/GDP-mannose_3,5-epimerase GDP-mannose 3,5-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.18 5.1.3.18] Known structural/functional Site: <scene name='pdbsite=AC1:Btb+Binding+Site+For+Chain+B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5A OCA].  
2C5A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5A OCA].  


==Reference==
==Reference==
Structure and function of GDP-mannose-3',5'-epimerase: an enzyme which performs three chemical reactions at the same active site., Major LL, Wolucka BA, Naismith JH, J Am Chem Soc. 2005 Dec 28;127(51):18309-20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16366586 16366586]
Structure and function of GDP-mannose-3',5'-epimerase: an enzyme which performs three chemical reactions at the same active site., Major LL, Wolucka BA, Naismith JH, J Am Chem Soc. 2005 Dec 28;127(51):18309-20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16366586 16366586]
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: GDP-mannose 3,5-epimerase]]
[[Category: GDP-mannose 3,5-epimerase]]
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[[Category: vitamin c]]
[[Category: vitamin c]]


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