2c5w: Difference between revisions

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[[Image:2c5w.gif|left|200px]]<br /><applet load="2c5w" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2c5w.gif|left|200px]]
caption="2c5w, resolution 2.55&Aring;" />
 
'''PENICILLIN-BINDING PROTEIN 1A (PBP-1A) ACYL-ENZYME COMPLEX (CEFOTAXIME) FROM STREPTOCOCCUS PNEUMONIAE'''<br />
{{Structure
|PDB= 2c5w |SIZE=350|CAPTION= <scene name='initialview01'>2c5w</scene>, resolution 2.55&Aring;
|SITE= <scene name='pdbsite=AC1:Pcz+Binding+Site+For+Chain+B'>AC1</scene>
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene> and <scene name='pdbligand=PCZ:PCNOTAXIME GROUP'>PCZ</scene>
|ACTIVITY=
|GENE=
}}
 
'''PENICILLIN-BINDING PROTEIN 1A (PBP-1A) ACYL-ENZYME COMPLEX (CEFOTAXIME) FROM STREPTOCOCCUS PNEUMONIAE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2C5W is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=EDO:'>EDO</scene> and <scene name='pdbligand=PCZ:'>PCZ</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Site: <scene name='pdbsite=AC1:Pcz+Binding+Site+For+Chain+B'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5W OCA].  
2C5W is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C5W OCA].  


==Reference==
==Reference==
Crystal structure of penicillin-binding protein 1a (PBP1a) reveals a mutational hotspot implicated in beta-lactam resistance in Streptococcus pneumoniae., Contreras-Martel C, Job V, Di Guilmi AM, Vernet T, Dideberg O, Dessen A, J Mol Biol. 2006 Jan 27;355(4):684-96. Epub 2005 Nov 9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16316661 16316661]
Crystal structure of penicillin-binding protein 1a (PBP1a) reveals a mutational hotspot implicated in beta-lactam resistance in Streptococcus pneumoniae., Contreras-Martel C, Job V, Di Guilmi AM, Vernet T, Dideberg O, Dessen A, J Mol Biol. 2006 Jan 27;355(4):684-96. Epub 2005 Nov 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16316661 16316661]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Streptococcus pneumoniae]]
[[Category: Streptococcus pneumoniae]]
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[[Category: peptidoglycan synthesis]]
[[Category: peptidoglycan synthesis]]


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