4ks7: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ks7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ks7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ks7 RCSB], [http://www.ebi.ac.uk/pdbsum/4ks7 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ks7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ks7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ks7 RCSB], [http://www.ebi.ac.uk/pdbsum/4ks7 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/PAK6_HUMAN PAK6_HUMAN]] Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.<ref>PMID:14573606</ref> <ref>PMID:20054820</ref> | |||
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== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
