2ca8: Difference between revisions

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[[Image:2ca8.gif|left|200px]]<br /><applet load="2ca8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ca8.gif|left|200px]]
caption="2ca8, resolution 2.49&Aring;" />
 
'''STRUCTURE OF SH28GST IN COMPLEX WITH GSH AT PH 6.0'''<br />
{{Structure
|PDB= 2ca8 |SIZE=350|CAPTION= <scene name='initialview01'>2ca8</scene>, resolution 2.49&Aring;
|SITE= <scene name='pdbsite=AC1:Pg4+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=GSW:D-GAMMA-GLUTAMYL-L-CYSTEINYLGLYCINE'>GSW</scene> and <scene name='pdbligand=PG4:TETRAETHYLENE GLYCOL'>PG4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18]
|GENE=
}}
 
'''STRUCTURE OF SH28GST IN COMPLEX WITH GSH AT PH 6.0'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2CA8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Schistosoma_haematobium Schistosoma haematobium] with <scene name='pdbligand=GSW:'>GSW</scene> and <scene name='pdbligand=PG4:'>PG4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] Known structural/functional Site: <scene name='pdbsite=AC1:Pg4+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA8 OCA].  
2CA8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Schistosoma_haematobium Schistosoma haematobium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA8 OCA].  


==Reference==
==Reference==
Probing the mechanism of GSH activation in Schistosoma haematobium glutathione-S-transferase by site-directed mutagenesis and X-ray crystallography., Baiocco P, Gourlay LJ, Angelucci F, Fontaine J, Herve M, Miele AE, Trottein F, Brunori M, Bellelli A, J Mol Biol. 2006 Jul 14;360(3):678-89. Epub 2006 Jun 2. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16777141 16777141]
Probing the mechanism of GSH activation in Schistosoma haematobium glutathione-S-transferase by site-directed mutagenesis and X-ray crystallography., Baiocco P, Gourlay LJ, Angelucci F, Fontaine J, Herve M, Miele AE, Trottein F, Brunori M, Bellelli A, J Mol Biol. 2006 Jul 14;360(3):678-89. Epub 2006 Jun 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16777141 16777141]
[[Category: Glutathione transferase]]
[[Category: Glutathione transferase]]
[[Category: Schistosoma haematobium]]
[[Category: Schistosoma haematobium]]
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[[Category: transferase]]
[[Category: transferase]]


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