2cbm: Difference between revisions

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[[Image:2cbm.gif|left|200px]]<br /><applet load="2cbm" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2cbm.gif|left|200px]]
caption="2cbm, resolution 2.03&Aring;" />
 
'''CRYSTAL STRUCTURE OF THE APO-FORM OF A NEOCARZINOSTATIN MUTANT EVOLVED TO BIND TESTOSTERONE.'''<br />
{{Structure
|PDB= 2cbm |SIZE=350|CAPTION= <scene name='initialview01'>2cbm</scene>, resolution 2.03&Aring;
|SITE= <scene name='pdbsite=AC1:Mes+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC ACID'>MES</scene>
|ACTIVITY=
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF THE APO-FORM OF A NEOCARZINOSTATIN MUTANT EVOLVED TO BIND TESTOSTERONE.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2CBM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_carzinostaticus Streptomyces carzinostaticus] with <scene name='pdbligand=MES:'>MES</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Mes+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CBM OCA].  
2CBM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_carzinostaticus Streptomyces carzinostaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CBM OCA].  


==Reference==
==Reference==
Structures of in vitro evolved binding sites on neocarzinostatin scaffold reveal unanticipated evolutionary pathways., Drevelle A, Graille M, Heyd B, Sorel I, Ulryck N, Pecorari F, Desmadril M, van Tilbeurgh H, Minard P, J Mol Biol. 2006 Apr 28;358(2):455-71. Epub 2006 Feb 20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16529771 16529771]
Structures of in vitro evolved binding sites on neocarzinostatin scaffold reveal unanticipated evolutionary pathways., Drevelle A, Graille M, Heyd B, Sorel I, Ulryck N, Pecorari F, Desmadril M, van Tilbeurgh H, Minard P, J Mol Biol. 2006 Apr 28;358(2):455-71. Epub 2006 Feb 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16529771 16529771]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Streptomyces carzinostaticus]]
[[Category: Streptomyces carzinostaticus]]
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[[Category: phage-display]]
[[Category: phage-display]]


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