2cfc: Difference between revisions

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[[Image:2cfc.gif|left|200px]]<br /><applet load="2cfc" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2cfc.gif|left|200px]]
caption="2cfc, resolution 1.8&Aring;" />
 
'''STRUCTURAL BASIS FOR STEREO SELECTIVITY IN THE (R)- AND (S)-HYDROXYPROPYLETHANE THIOSULFONATE DEHYDROGENASES'''<br />
{{Structure
|PDB= 2cfc |SIZE=350|CAPTION= <scene name='initialview01'>2cfc</scene>, resolution 1.8&Aring;
|SITE= <scene name='pdbsite=AC1:Kpc+Binding+Site+For+Chain+D'>AC1</scene>
|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene> and <scene name='pdbligand=KPC:(2-[2-KETOPROPYLTHIO]ETHANESULFONATE'>KPC</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/2-(R)-hydroxypropyl-CoM_dehydrogenase 2-(R)-hydroxypropyl-CoM dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.268 1.1.1.268]
|GENE=
}}
 
'''STRUCTURAL BASIS FOR STEREO SELECTIVITY IN THE (R)- AND (S)-HYDROXYPROPYLETHANE THIOSULFONATE DEHYDROGENASES'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2CFC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Xanthobacter_autotrophicus Xanthobacter autotrophicus] with <scene name='pdbligand=NAD:'>NAD</scene> and <scene name='pdbligand=KPC:'>KPC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/2-(R)-hydroxypropyl-CoM_dehydrogenase 2-(R)-hydroxypropyl-CoM dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.268 1.1.1.268] Known structural/functional Site: <scene name='pdbsite=AC1:Kpc+Binding+Site+For+Chain+D'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFC OCA].  
2CFC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Xanthobacter_autotrophicus Xanthobacter autotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFC OCA].  


==Reference==
==Reference==
Structural basis for stereoselectivity in the (R)- and (S)-hydroxypropylthioethanesulfonate dehydrogenases., Krishnakumar AM, Nocek BP, Clark DD, Ensign SA, Peters JW, Biochemistry. 2006 Jul 25;45(29):8831-40. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16846226 16846226]
Structural basis for stereoselectivity in the (R)- and (S)-hydroxypropylthioethanesulfonate dehydrogenases., Krishnakumar AM, Nocek BP, Clark DD, Ensign SA, Peters JW, Biochemistry. 2006 Jul 25;45(29):8831-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16846226 16846226]
[[Category: 2-(R)-hydroxypropyl-CoM dehydrogenase]]
[[Category: 2-(R)-hydroxypropyl-CoM dehydrogenase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: oxidoreductase]]
[[Category: oxidoreductase]]


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