2chz: Difference between revisions

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[[Image:2chz.gif|left|200px]]<br /><applet load="2chz" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2chz.gif|left|200px]]
caption="2chz, resolution 2.60&Aring;" />
 
'''A PHARMACOLOGICAL MAP OF THE PI3-K FAMILY DEFINES A ROLE FOR P110ALPHA IN SIGNALING: THE STRUCTURE OF COMPLEX OF PHOSPHOINOSITIDE 3-KINASE GAMMA WITH INHIBITOR PIK-93'''<br />
{{Structure
|PDB= 2chz |SIZE=350|CAPTION= <scene name='initialview01'>2chz</scene>, resolution 2.60&Aring;
|SITE= <scene name='pdbsite=AC1:093+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=093:N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE'>093</scene>
|ACTIVITY=
|GENE=
}}
 
'''A PHARMACOLOGICAL MAP OF THE PI3-K FAMILY DEFINES A ROLE FOR P110ALPHA IN SIGNALING: THE STRUCTURE OF COMPLEX OF PHOSPHOINOSITIDE 3-KINASE GAMMA WITH INHIBITOR PIK-93'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2CHZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=093:'>093</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:093+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHZ OCA].  
2CHZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CHZ OCA].  


==Reference==
==Reference==
A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling., Knight ZA, Gonzalez B, Feldman ME, Zunder ER, Goldenberg DD, Williams O, Loewith R, Stokoe D, Balla A, Toth B, Balla T, Weiss WA, Williams RL, Shokat KM, Cell. 2006 May 19;125(4):733-47. Epub 2006 Apr 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16647110 16647110]
A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling., Knight ZA, Gonzalez B, Feldman ME, Zunder ER, Goldenberg DD, Williams O, Loewith R, Stokoe D, Balla A, Toth B, Balla T, Weiss WA, Williams RL, Shokat KM, Cell. 2006 May 19;125(4):733-47. Epub 2006 Apr 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16647110 16647110]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transferase]]
[[Category: transferase]]


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