2cpu: Difference between revisions

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[[Image:2cpu.jpg|left|200px]]~~<br /><applet load~~="2cpu~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:2cpu.jpg|left|200px]]

~~caption="~~2cpu, resolution 2.Å" />

'''SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT'''~~<br />~~

{{Structure

|PDB= 2cpu |SIZE=350|CAPTION= <scene name='initialview01'>2cpu</scene>, resolution 2.Å

|SITE=

|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=CL:CHLORIDE ION'>CL</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Alpha-amylase Alpha-amylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.1 3.2.1.1]

|GENE=

}}

'''SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT'''

==Overview==

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==About this Structure==

2CPU is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens~~] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=CL:'>CL</scene> as [http://en.wikipedia.org/wiki/ligands ligands~~]. ~~Active as [http://en.wikipedia.org/wiki/Alpha-amylase Alpha-amylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.1 3.2.1.1]~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CPU OCA].

2CPU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CPU OCA].

==Reference==

Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques., Brayer GD, Sidhu G, Maurus R, Rydberg EH, Braun C, Wang Y, Nguyen NT, Overall CM, Withers SG, Biochemistry. 2000 Apr 25;39(16):4778-91. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~10769135 10769135]

Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques., Brayer GD, Sidhu G, Maurus R, Rydberg EH, Braun C, Wang Y, Nguyen NT, Overall CM, Withers SG, Biochemistry. 2000 Apr 25;39(16):4778-91. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10769135 10769135]

[[Category: Alpha-amylase]]

[[Category: Homo sapiens]]

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[[Category: pancreatic]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21~~ 16:51:13 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:18:31 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2cpu.jpg|left|200px]]<br /><applet load="2cpu" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2cpu.jpg|left|200px]]
-caption="2cpu, resolution 2.&Aring;" />
-'''SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT'''<br />
+ {{Structure
+|PDB= 2cpu |SIZE=350|CAPTION= <scene name='initialview01'>2cpu</scene>, resolution 2.&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=CL:CHLORIDE ION'>CL</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Alpha-amylase Alpha-amylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.1 3.2.1.1]
+|GENE=
+}}
+'''SUBSITE MAPPING OF THE ACTIVE SITE OF HUMAN PANCREATIC ALPHA-AMYLASE USING SUBSTRATES, THE PHARMACOLOGICAL INHIBITOR ACARBOSE, AND AN ACTIVE SITE VARIANT'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-CPU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=CL:'>CL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alpha-amylase Alpha-amylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.1 3.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CPU OCA].
+CPU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CPU OCA].
 ==Reference==
-Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques., Brayer GD, Sidhu G, Maurus R, Rydberg EH, Braun C, Wang Y, Nguyen NT, Overall CM, Withers SG, Biochemistry. 2000 Apr 25;39(16):4778-91. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10769135 10769135]
+Subsite mapping of the human pancreatic alpha-amylase active site through structural, kinetic, and mutagenesis techniques., Brayer GD, Sidhu G, Maurus R, Rydberg EH, Braun C, Wang Y, Nguyen NT, Overall CM, Withers SG, Biochemistry. 2000 Apr 25;39(16):4778-91. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10769135 10769135]
 [[Category: Alpha-amylase]]
 [[Category: Homo sapiens]]
@@ Line 33: / Line 42: @@
 [[Category: pancreatic]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:51:13 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:18:31 2008''