3k6p: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k6p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k6p RCSB], [http://www.ebi.ac.uk/pdbsum/3k6p PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3k6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k6p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3k6p RCSB], [http://www.ebi.ac.uk/pdbsum/3k6p PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/ERR1_HUMAN ERR1_HUMAN]] Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism.<ref>PMID:9271417</ref> <ref>PMID:12522104</ref> <ref>PMID:16150865</ref> <ref>PMID:17676930</ref> <ref>PMID:18063693</ref> | |||
==See Also== | ==See Also== | ||
*[[Estrogen-related receptor|Estrogen-related receptor]] | *[[Estrogen-related receptor|Estrogen-related receptor]] | ||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 10:03, 25 December 2014
Estrogen Related Receptor alpha in Complex with an Ether Based Ligand
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