2cvd: Difference between revisions

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[[Image:2cvd.gif|left|200px]]<br /><applet load="2cvd" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2cvd.gif|left|200px]]
caption="2cvd, resolution 1.45&Aring;" />
 
'''Crystal structure analysis of human hematopoietic prostaglandin D synthase complexed with HQL-79'''<br />
{{Structure
|PDB= 2cvd |SIZE=350|CAPTION= <scene name='initialview01'>2cvd</scene>, resolution 1.45&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=HQL:4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE'>HQL</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY=
|GENE=
}}
 
'''Crystal structure analysis of human hematopoietic prostaglandin D synthase complexed with HQL-79'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2CVD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=GSH:'>GSH</scene>, <scene name='pdbligand=HQL:'>HQL</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CVD OCA].  
2CVD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CVD OCA].  


==Reference==
==Reference==
Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase., Aritake K, Kado Y, Inoue T, Miyano M, Urade Y, J Biol Chem. 2006 Jun 2;281(22):15277-86. Epub 2006 Mar 17. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16547010 16547010]
Structural and functional characterization of HQL-79, an orally selective inhibitor of human hematopoietic prostaglandin D synthase., Aritake K, Kado Y, Inoue T, Miyano M, Urade Y, J Biol Chem. 2006 Jun 2;281(22):15277-86. Epub 2006 Mar 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16547010 16547010]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: isomerase]]
[[Category: isomerase]]


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