2d2d: Difference between revisions

Line 1:

[[Image:2d2d.gif|left|200px]]~~<br /><applet load~~="2d2d~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:2d2d.gif|left|200px]]

~~caption="~~2d2d, resolution 2.7Å" />

'''Crystal Structure Of SARS-CoV Mpro in Complex with an Inhibitor I2'''~~<br />~~

{{Structure

|PDB= 2d2d |SIZE=350|CAPTION= <scene name='initialview01'>2d2d</scene>, resolution 2.7Å

|SITE=

|LIGAND= <scene name='pdbligand=ENB:ETHYL (2E,4S)-4-[((2R)-2-{[N-(TERT-BUTOXYCARBONYL)-L-VALYL]AMINO}-2-PHENYLETHANOYL)AMINO]-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENT-2-ENOATE'>ENB</scene>

|ACTIVITY=

|GENE=

}}

'''Crystal Structure Of SARS-CoV Mpro in Complex with an Inhibitor I2'''

==Overview==

Line 7:

Line 16:

==About this Structure==

2D2D is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_sars_coronavirus Human sars coronavirus~~] with <scene name='pdbligand=ENB:'>ENB</scene> as [http://en.wikipedia.org/wiki/ligand ligand~~]. This structure supersedes the now removed PDB entry 1WNQ. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2D OCA].

2D2D is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_sars_coronavirus Human sars coronavirus]. This structure supersedes the now removed PDB entry 1WNQ. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2D OCA].

==Reference==

Design of wide-spectrum inhibitors targeting coronavirus main proteases., Yang H, Xie W, Xue X, Yang K, Ma J, Liang W, Zhao Q, Zhou Z, Pei D, Ziebuhr J, Hilgenfeld R, Yuen KY, Wong L, Gao G, Chen S, Chen Z, Ma D, Bartlam M, Rao Z, PLoS Biol. 2005 Oct;3(10):e324. Epub 2005 Sep 6. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~16128623 16128623]

Design of wide-spectrum inhibitors targeting coronavirus main proteases., Yang H, Xie W, Xue X, Yang K, Ma J, Liang W, Zhao Q, Zhou Z, Pei D, Ziebuhr J, Hilgenfeld R, Yuen KY, Wong L, Gao G, Chen S, Chen Z, Ma D, Bartlam M, Rao Z, PLoS Biol. 2005 Oct;3(10):e324. Epub 2005 Sep 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16128623 16128623]

[[Category: Human sars coronavirus]]

[[Category: Single protein]]

Line 21:

Line 30:

[[Category: Yang, K.]]

[[Category: ENB]]

[[Category: anti-parallel a-~~helices~~]]

[[Category: anti-parallel a-helice]]

[[Category: anti-parallel b-barrel]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21~~ 16:54:40 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:22:28 2008''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-[[Image:2d2d.gif|left|200px]]<br /><applet load="2d2d" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2d2d.gif|left|200px]]
-caption="2d2d, resolution 2.7&Aring;" />
-'''Crystal Structure Of SARS-CoV Mpro in Complex with an Inhibitor I2'''<br />
+ {{Structure
+|PDB= 2d2d |SIZE=350|CAPTION= <scene name='initialview01'>2d2d</scene>, resolution 2.7&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=ENB:ETHYL (2E,4S)-4-[((2R)-2-{[N-(TERT-BUTOXYCARBONYL)-L-VALYL]AMINO}-2-PHENYLETHANOYL)AMINO]-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENT-2-ENOATE'>ENB</scene>
+|ACTIVITY=
+|GENE=
+}}
+'''Crystal Structure Of SARS-CoV Mpro in Complex with an Inhibitor I2'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-D2D is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_sars_coronavirus Human sars coronavirus] with <scene name='pdbligand=ENB:'>ENB</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. This structure supersedes the now removed PDB entry 1WNQ. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2D OCA].
+D2D is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_sars_coronavirus Human sars coronavirus]. This structure supersedes the now removed PDB entry 1WNQ. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D2D OCA].
 ==Reference==
-Design of wide-spectrum inhibitors targeting coronavirus main proteases., Yang H, Xie W, Xue X, Yang K, Ma J, Liang W, Zhao Q, Zhou Z, Pei D, Ziebuhr J, Hilgenfeld R, Yuen KY, Wong L, Gao G, Chen S, Chen Z, Ma D, Bartlam M, Rao Z, PLoS Biol. 2005 Oct;3(10):e324. Epub 2005 Sep 6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16128623 16128623]
+Design of wide-spectrum inhibitors targeting coronavirus main proteases., Yang H, Xie W, Xue X, Yang K, Ma J, Liang W, Zhao Q, Zhou Z, Pei D, Ziebuhr J, Hilgenfeld R, Yuen KY, Wong L, Gao G, Chen S, Chen Z, Ma D, Bartlam M, Rao Z, PLoS Biol. 2005 Oct;3(10):e324. Epub 2005 Sep 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16128623 16128623]
 [[Category: Human sars coronavirus]]
 [[Category: Single protein]]
@@ Line 21: / Line 30: @@
 [[Category: Yang, K.]]
 [[Category: ENB]]
-[[Category: anti-parallel a-helices]]
+[[Category: anti-parallel a-helice]]
 [[Category: anti-parallel b-barrel]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:54:40 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:22:28 2008''