4jdb: Difference between revisions
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==Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with MII-5-005== | |||
<StructureSection load='4jdb' size='340' side='right' caption='[[4jdb]], [[Resolution|resolution]] 1.82Å' scene=''> | |||
== Structural highlights == | |||
==Function== | <table><tr><td colspan='2'>[[4jdb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycc Trycc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JDB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JDB FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=JDB:5-[2-(7-METHOXYNAPHTHALEN-2-YL)ETHYL]-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC+ACID'>JDB</scene>, <scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3w1a|3w1a]], [[3w1l|3w1l]], [[3w1m|3w1m]], [[3w1n|3w1n]], [[3w1p|3w1p]], [[3w1q|3w1q]], [[3w1r|3w1r]], [[3w1t|3w1t]], [[3w1u|3w1u]], [[3w1x|3w1x]], [[3w22|3w22]], [[3w23|3w23]], [[3w2j|3w2j]], [[3w2k|3w2k]], [[3w2l|3w2l]], [[3w2m|3w2m]], [[3w2n|3w2n]], [[3w2u|3w2u]], [[4jd4|4jd4]]</td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PyrD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353153 TRYCC])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jdb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jdb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jdb RCSB], [http://www.ebi.ac.uk/pdbsum/4jdb PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. | [[http://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. | ||
__TOC__ | |||
</StructureSection> | |||
[[ | [[Category: Trycc]] | ||
[[Category: Aoki, T | [[Category: Aoki, T]] | ||
[[Category: Balogun, E O | [[Category: Balogun, E O]] | ||
[[Category: Harada, S | [[Category: Harada, S]] | ||
[[Category: Hashimoto, S | [[Category: Hashimoto, S]] | ||
[[Category: Honma, T | [[Category: Honma, T]] | ||
[[Category: Iida, M | [[Category: Iida, M]] | ||
[[Category: Inaoka, D K | [[Category: Inaoka, D K]] | ||
[[Category: Inoue, M | [[Category: Inoue, M]] | ||
[[Category: Kita, K | [[Category: Kita, K]] | ||
[[Category: Kuranaga, T | [[Category: Kuranaga, T]] | ||
[[Category: Lee, N | [[Category: Lee, N]] | ||
[[Category: Matsuoka, S | [[Category: Matsuoka, S]] | ||
[[Category: Nara, T | [[Category: Nara, T]] | ||
[[Category: Sakamoto, K | [[Category: Sakamoto, K]] | ||
[[Category: Shiba, T | [[Category: Shiba, T]] | ||
[[Category: Suzuki, S | [[Category: Suzuki, S]] | ||
[[Category: Tabuchi, T | [[Category: Tabuchi, T]] | ||
[[Category: Tanaka, A | [[Category: Tanaka, A]] | ||
[[Category: Cytosol]] | [[Category: Cytosol]] | ||
[[Category: Dihydroorotate/orotate and fumarate/succinate binding]] | [[Category: Dihydroorotate/orotate and fumarate/succinate binding]] | ||
