4q5j: Difference between revisions

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q5j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q5j RCSB], [http://www.ebi.ac.uk/pdbsum/4q5j PDBsum]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/BRI1_ARATH BRI1_ARATH]] Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Phosphorylates BRI1-associated receptor kinase 1 (BAK1), Transthyretin-Like protein (TTL) and SERK1 on 'Ser-299' and 'Thr-462' in vitro. May have a guanylyl cyclase activity.<ref>PMID:10557222</ref> <ref>PMID:10938344</ref> <ref>PMID:17138891</ref> <ref>PMID:17520012</ref> <ref>PMID:18694562</ref> <ref>PMID:19124768</ref> [[http://www.uniprot.org/uniprot/BKI1_ARATH BKI1_ARATH]] Negative regulator of brassinosteroid signaling. When associated to the membrane, limits the interaction of BRI1 with BAK1 by binding to the kinase-inactive form of BRI1.<ref>PMID:16857903</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Chen, L.]]

[[Category: Chen, L]]

[[Category: Wang, J.]]

[[Category: Wang, J]]

[[Category: Wang, Z X.]]

[[Category: Wang, Z X]]

[[Category: Wu, J W.]]

[[Category: Wu, J W]]

[[Category: Atp binding]]

[[Category: Kinase domain]]

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@@ Line 8: / Line 8: @@
 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q5j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q5j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q5j RCSB], [http://www.ebi.ac.uk/pdbsum/4q5j PDBsum]</span></td></tr>
 </table>
+== Function ==
+[[http://www.uniprot.org/uniprot/BRI1_ARATH BRI1_ARATH]] Receptor with a dual specificity kinase activity acting on both serine/threonine- and tyrosine-containing substrates. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development, including expression of light- and stress-regulated genes, promotion of cell elongation, normal leaf and chloroplast senescence, and flowering. Binds brassinolide, and less effectively castasterone, but not 2,3,22,23-O-tetramethylbrassinolide or ecdysone. May be involved in a feedback regulation of brassinosteroid biosynthesis. Phosphorylates BRI1-associated receptor kinase 1 (BAK1), Transthyretin-Like protein (TTL) and SERK1 on 'Ser-299' and 'Thr-462' in vitro. May have a guanylyl cyclase activity.<ref>PMID:10557222</ref> <ref>PMID:10938344</ref> <ref>PMID:17138891</ref> <ref>PMID:17520012</ref> <ref>PMID:18694562</ref> <ref>PMID:19124768</ref>  [[http://www.uniprot.org/uniprot/BKI1_ARATH BKI1_ARATH]] Negative regulator of brassinosteroid signaling. When associated to the membrane, limits the interaction of BRI1 with BAK1 by binding to the kinase-inactive form of BRI1.<ref>PMID:16857903</ref>
+== References ==
+<references/>
 __TOC__
 </StructureSection>
-[[Category: Chen, L.]]
+[[Category: Chen, L]]
-[[Category: Wang, J.]]
+[[Category: Wang, J]]
-[[Category: Wang, Z X.]]
+[[Category: Wang, Z X]]
-[[Category: Wu, J W.]]
+[[Category: Wu, J W]]
 [[Category: Atp binding]]
 [[Category: Kinase domain]]