1yo5: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1yo5]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YO5 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1yo5]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YO5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1YO5 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDEF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDEF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yo5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yo5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yo5 RCSB], [http://www.ebi.ac.uk/pdbsum/1yo5 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1yo5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yo5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1yo5 RCSB], [http://www.ebi.ac.uk/pdbsum/1yo5 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/SPDEF_HUMAN SPDEF_HUMAN]] May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter.<ref>PMID:10625666</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Balderman, S | [[Category: Balderman, S]] | ||
[[Category: Fayazi, Z | [[Category: Fayazi, Z]] | ||
[[Category: Feng, L | [[Category: Feng, L]] | ||
[[Category: Ghosh, D | [[Category: Ghosh, D]] | ||
[[Category: Gulick, A M | [[Category: Gulick, A M]] | ||
[[Category: Liu, Y | [[Category: Liu, Y]] | ||
[[Category: Said, M | [[Category: Said, M]] | ||
[[Category: Wang, Y | [[Category: Wang, Y]] | ||
[[Category: Double helix]] | [[Category: Double helix]] | ||
[[Category: Et]] | [[Category: Et]] | ||
[[Category: Protein-dna complex]] | [[Category: Protein-dna complex]] | ||
[[Category: Transcription-dna complex]] | [[Category: Transcription-dna complex]] | ||