2dhf: Difference between revisions

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[[Image:2dhf.gif|left|200px]]<br /><applet load="2dhf" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2dhf.gif|left|200px]]
caption="2dhf, resolution 2.3&Aring;" />
 
'''CRYSTAL STRUCTURES OF RECOMBINANT HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND 5-DEAZOFOLATE'''<br />
{{Structure
|PDB= 2dhf |SIZE=350|CAPTION= <scene name='initialview01'>2dhf</scene>, resolution 2.3&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=DZF:5-DEAZAFOLIC ACID'>DZF</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3]
|GENE=
}}
 
'''CRYSTAL STRUCTURES OF RECOMBINANT HUMAN DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND 5-DEAZOFOLATE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2DHF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=DZF:'>DZF</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DHF OCA].  
2DHF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DHF OCA].  


==Reference==
==Reference==
Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate., Davies JF 2nd, Delcamp TJ, Prendergast NJ, Ashford VA, Freisheim JH, Kraut J, Biochemistry. 1990 Oct 9;29(40):9467-79. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=2248959 2248959]
Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate., Davies JF 2nd, Delcamp TJ, Prendergast NJ, Ashford VA, Freisheim JH, Kraut J, Biochemistry. 1990 Oct 9;29(40):9467-79. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2248959 2248959]
[[Category: Dihydrofolate reductase]]
[[Category: Dihydrofolate reductase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: oxido-reductase]]
[[Category: oxido-reductase]]


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