2of6: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2of6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/West_nile_virus West nile virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OF6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OF6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2of6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/West_nile_virus West nile virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OF6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OF6 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2of6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2of6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2of6 RCSB], [http://www.ebi.ac.uk/pdbsum/2of6 PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2of6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2of6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2of6 RCSB], [http://www.ebi.ac.uk/pdbsum/2of6 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/Q9Q6P4_WNV Q9Q6P4_WNV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS011998_004_099774] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: West nile virus]] | [[Category: West nile virus]] | ||
[[Category: Chipman, P R | [[Category: Chipman, P R]] | ||
[[Category: Kaufmann, B | [[Category: Kaufmann, B]] | ||
[[Category: Kuhn, R J | [[Category: Kuhn, R J]] | ||
[[Category: Rossmann, M G | [[Category: Rossmann, M G]] | ||
[[Category: Zhang, Y | [[Category: Zhang, Y]] | ||
[[Category: Em immature flavivirus west nile]] | [[Category: Em immature flavivirus west nile]] | ||
[[Category: Icosahedral virus]] | [[Category: Icosahedral virus]] | ||
[[Category: Virus]] | [[Category: Virus]] | ||
