1a12: Difference between revisions

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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a12 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a12 RCSB], [http://www.ebi.ac.uk/pdbsum/1a12 PDBsum]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a12 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1a12 RCSB], [http://www.ebi.ac.uk/pdbsum/1a12 PDBsum]</span></td></tr>
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== Function ==
[[http://www.uniprot.org/uniprot/RCC1_HUMAN RCC1_HUMAN]] Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.<ref>PMID:1944575</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]