3w3d

Crystal structure of smooth muscle G actin DNase I complex

spinqualitylabelsall models 3w3d, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3w3d is a 2 chain structure with sequence from Bos taurus and Chick. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: ATP, BMA, CA, MAN, NAG NonStd Res: HIC Activity: Deoxyribonuclease I, with EC number 3.1.21.1 Resources: FirstGlance, OCA, RCSB, PDBsum Function [DNAS1_BOVIN] Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization (By similarity). Publication Abstract from PubMed X-ray diffraction photographs of a chicken gizzard G-actin.DNase I complex crystal have been recorded using the synchrotron radiation beam emitted by the Synchrotron Radiation Source at Daresbury and the Photon Factory at Tsukuba. The resolution limit was extended to 2.4 A and the exposure time was reduced approximately by a factor of 10, when data recorded at the Photon Factory, were compared with those recorded with a conventional rotating-anode source. Using a newly designed Weissenberg camera equipped with a multi-layer line screen, the diffraction data in a 36 degrees oscillation range were recorded on a single film up to 3.5 A resolution. X-ray diffraction photographs of chicken gizzard G-actin.DNase I complex crystals taken with synchrotron radiation.,Sakabe N, Kamiya N, Sakabe K, Kondo H J Biochem. 1984 Mar;95(3):887-90. PMID:6233270 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See Also Actin

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