1jw2: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1jw2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JW2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JW2 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1jw2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JW2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JW2 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jw2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jw2 RCSB], [http://www.ebi.ac.uk/pdbsum/1jw2 PDBsum], [http://www.topsan.org/Proteins/NESGC/1jw2 TOPSAN]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jw2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jw2 RCSB], [http://www.ebi.ac.uk/pdbsum/1jw2 PDBsum], [http://www.topsan.org/Proteins/NESGC/1jw2 TOPSAN]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/HHA_ECOLI HHA_ECOLI]] Down-regulates hemolysin production and can also stimulate transposition events in vivo. Binds DNA and influences DNA topology in response to environmental stimuli. Involved in persister cell formation, acting downstream of mRNA interferase (toxin) MqsR. Decreases biofilm formation by repressing the transcription of fimbrial genes fimA and ihfA, and by repressing the transcription of tRNAs corresponding to rare codons, which are abundant in type 1 fimbrial genes.<ref>PMID:1956303</ref> <ref>PMID:16317765</ref> <ref>PMID:18545668</ref> <ref>PMID:19909729</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Arrowsmith, C H | [[Category: Arrowsmith, C H]] | ||
[[Category: Chang, X | [[Category: Chang, X]] | ||
[[Category: Edwards, A M | [[Category: Edwards, A M]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Savchenko, A | [[Category: Savchenko, A]] | ||
[[Category: Yee, A | [[Category: Yee, A]] | ||
[[Category: Gene regulation]] | [[Category: Gene regulation]] | ||
[[Category: Hemolysin expression modulating protein]] | [[Category: Hemolysin expression modulating protein]] | ||
[[Category: Hha]] | [[Category: Hha]] | ||
[[Category: Nesg]] | [[Category: Nesg]] | ||
[[Category: Ocsp]] | [[Category: Ocsp]] | ||
[[Category: Protein structure initiative | [[Category: PSI, Protein structure initiative]] | ||
