2e14: Difference between revisions

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[[Image:2e14.jpg|left|200px]]<br /><applet load="2e14" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2e14.jpg|left|200px]]
caption="2e14, resolution 3.0&Aring;" />
 
'''The structure of ERK2 in complex with FR148083'''<br />
{{Structure
|PDB= 2e14 |SIZE=350|CAPTION= <scene name='initialview01'>2e14</scene>, resolution 3.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=FRR:(3R,5Z,8S,9S,11E)-8,9,16-TRIHYDROXY-14-METHOXY-3-METHYL-3,4,9,10-TETRAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,7(8H)-DIONE'>FRR</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24]
|GENE=
}}
 
'''The structure of ERK2 in complex with FR148083'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2E14 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=FRR:'>FRR</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Mitogen-activated_protein_kinase Mitogen-activated protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.24 2.7.11.24] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E14 OCA].  
2E14 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E14 OCA].  


==Reference==
==Reference==
Role of a cysteine residue in the active site of ERK and the MAPKK family., Ohori M, Kinoshita T, Yoshimura S, Warizaya M, Nakajima H, Miyake H, Biochem Biophys Res Commun. 2007 Feb 16;353(3):633-7. Epub 2006 Dec 20. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17194451 17194451]
Role of a cysteine residue in the active site of ERK and the MAPKK family., Ohori M, Kinoshita T, Yoshimura S, Warizaya M, Nakajima H, Miyake H, Biochem Biophys Res Commun. 2007 Feb 16;353(3):633-7. Epub 2006 Dec 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17194451 17194451]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mitogen-activated protein kinase]]
[[Category: Mitogen-activated protein kinase]]
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[[Category: transferase]]
[[Category: transferase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:04:50 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:33:54 2008''
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