1i8d: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1i8d]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I8D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1I8D FirstGlance]. <br>
<table><tr><td colspan='2'>[[1i8d]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I8D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1I8D FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACTERIA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACTERIA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Riboflavin_synthase Riboflavin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.9 2.5.1.9] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Riboflavin_synthase Riboflavin synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.9 2.5.1.9] </span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i8d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1i8d RCSB], [http://www.ebi.ac.uk/pdbsum/1i8d PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i8d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1i8d RCSB], [http://www.ebi.ac.uk/pdbsum/1i8d PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/RISA_ECOLI RISA_ECOLI]] Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Riboflavin synthase]]
[[Category: Riboflavin synthase]]
[[Category: Calabrese, J C.]]
[[Category: Calabrese, J C]]
[[Category: Jordan, D B.]]
[[Category: Jordan, D B]]
[[Category: Liao, D I.]]
[[Category: Liao, D I]]
[[Category: Viitanen, P V.]]
[[Category: Viitanen, P V]]
[[Category: Wawrzak, Z.]]
[[Category: Wawrzak, Z]]
[[Category: Antimicrobial target]]
[[Category: Antimicrobial target]]
[[Category: Escherichia coli]]
[[Category: Riboflavin biosynthesis]]
[[Category: Riboflavin biosynthesis]]
[[Category: Riboflavin synthase]]
[[Category: Structure-based design]]
[[Category: Structure-based design]]
[[Category: Transferase]]
[[Category: Transferase]]