4fl6: Difference between revisions
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==Crystal structure of the complex of the 3-MBT repeat domain of L3MBTL3 and UNC1215== | |||
<StructureSection load='4fl6' size='340' side='right' caption='[[4fl6]], [[Resolution|resolution]] 2.55Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4fl6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FL6 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene>, <scene name='pdbligand=UWN:[2-(PHENYLAMINO)BENZENE-1,4-DIYL]BIS{[4-(PYRROLIDIN-1-YL)PIPERIDIN-1-YL]METHANONE}'>UWN</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIAA1798, L3MBTL3, MBT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fl6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fl6 RCSB], [http://www.ebi.ac.uk/pdbsum/4fl6 PDBsum]</span></td></tr> | |||
== | </table> | ||
[[4fl6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FL6 OCA]. | == Function == | ||
[[http://www.uniprot.org/uniprot/LMBL3_HUMAN LMBL3_HUMAN]] Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C H | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C | [[Category: Bountra, C]] | ||
[[Category: Brown, P J | [[Category: Brown, P J]] | ||
[[Category: Dong, A | [[Category: Dong, A]] | ||
[[Category: Edwards, A M | [[Category: Edwards, A M]] | ||
[[Category: Frye, S V | [[Category: Frye, S V]] | ||
[[Category: Graslund, S | [[Category: Graslund, S]] | ||
[[Category: Ingerman, L A | [[Category: Ingerman, L A]] | ||
[[Category: Ravichandran, M | [[Category: Ravichandran, M]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Tempel, W | [[Category: Tempel, W]] | ||
[[Category: Zhong, N | [[Category: Zhong, N]] | ||
[[Category: Chromatin modification]] | [[Category: Chromatin modification]] | ||
[[Category: Mbt repeat]] | [[Category: Mbt repeat]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription repression]] | [[Category: Transcription repression]] | ||
