2e93: Difference between revisions

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[[Image:2e93.jpg|left|200px]]<br /><applet load="2e93" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2e93.jpg|left|200px]]
caption="2e93, resolution 2.12&Aring;" />
 
'''S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with BPH-629'''<br />
{{Structure
|PDB= 2e93 |SIZE=350|CAPTION= <scene name='initialview01'>2e93</scene>, resolution 2.12&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=B29:[2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID'>B29</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Trans-hexaprenyltranstransferase Trans-hexaprenyltranstransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.30 2.5.1.30]
|GENE=
}}
 
'''S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with BPH-629'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2E93 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=B29:'>B29</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Trans-hexaprenyltranstransferase Trans-hexaprenyltranstransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.30 2.5.1.30] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E93 OCA].  
2E93 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E93 OCA].  


==Reference==
==Reference==
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases., Guo RT, Cao R, Liang PH, Ko TP, Chang TH, Hudock MP, Jeng WY, Chen CK, Zhang Y, Song Y, Kuo CJ, Yin F, Oldfield E, Wang AH, Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10022-7. Epub 2007 May 29. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17535895 17535895]
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases., Guo RT, Cao R, Liang PH, Ko TP, Chang TH, Hudock MP, Jeng WY, Chen CK, Zhang Y, Song Y, Kuo CJ, Yin F, Oldfield E, Wang AH, Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10022-7. Epub 2007 May 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17535895 17535895]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: prenyltransferase]]
[[Category: prenyltransferase]]


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