2qgn: Difference between revisions
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==Crystal structure of tRNA isopentenylpyrophosphate transferase (BH2366) from Bacillus halodurans, Northeast Structural Genomics Consortium target BhR41.== | |||
<StructureSection load='2qgn' size='340' side='right' caption='[[2qgn]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2qgn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans_c-125 Bacillus halodurans c-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QGN FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">miaA, BH2366 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272558 Bacillus halodurans C-125])</td></tr> | |||
== | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_dimethylallyltransferase tRNA dimethylallyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.75 2.5.1.75] </span></td></tr> | ||
[[2qgn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_halodurans_c-125 Bacillus halodurans c-125]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QGN OCA]. | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qgn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qgn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2qgn RCSB], [http://www.ebi.ac.uk/pdbsum/2qgn PDBsum]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/MIAA_BACHD MIAA_BACHD]] Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qg/2qgn_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bacillus halodurans c-125]] | [[Category: Bacillus halodurans c-125]] | ||
[[Category: TRNA dimethylallyltransferase]] | [[Category: TRNA dimethylallyltransferase]] | ||
[[Category: Abashidze, M | [[Category: Abashidze, M]] | ||
[[Category: Acton, T B | [[Category: Acton, T B]] | ||
[[Category: Baran, M C | [[Category: Baran, M C]] | ||
[[Category: Cunningham, K | [[Category: Cunningham, K]] | ||
[[Category: Forouhar, F | [[Category: Forouhar, F]] | ||
[[Category: Hunt, J F | [[Category: Hunt, J F]] | ||
[[Category: Janjua, H | [[Category: Janjua, H]] | ||
[[Category: Liu, J | [[Category: Liu, J]] | ||
[[Category: Ma, L-C | [[Category: Ma, L-C]] | ||
[[Category: Montelione, G T | [[Category: Montelione, G T]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Neely, H | [[Category: Neely, H]] | ||
[[Category: Rost, B | [[Category: Rost, B]] | ||
[[Category: Seetharaman, J | [[Category: Seetharaman, J]] | ||
[[Category: Shastry, R | [[Category: Shastry, R]] | ||
[[Category: Tong, L | [[Category: Tong, L]] | ||
[[Category: Xiao, R | [[Category: Xiao, R]] | ||
[[Category: Alpha-beta protein]] | [[Category: Alpha-beta protein]] | ||
[[Category: Nesg]] | [[Category: Nesg]] | ||
[[Category: | [[Category: PSI, Protein structure initiative]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
