4ddp: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ddp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DDP FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ddp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DDP FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BECN1, GT197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BECN1, GT197 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ddp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ddp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ddp RCSB], [http://www.ebi.ac.uk/pdbsum/4ddp PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ddp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ddp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ddp RCSB], [http://www.ebi.ac.uk/pdbsum/4ddp PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/BECN1_HUMAN BECN1_HUMAN]] Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.<ref>PMID:20208530</ref> 
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Choi, W Y.]]
[[Category: Choi, W Y]]
[[Category: Huang, W J.]]
[[Category: Huang, W J]]
[[Category: Shi, Y G.]]
[[Category: Shi, Y G]]
[[Category: Wang, J W.]]
[[Category: Wang, J W]]
[[Category: Autophagy]]
[[Category: Autophagy]]
[[Category: Beclin 1]]
[[Category: Beclin 1]]

Revision as of 17:30, 25 December 2014

crystal structure of Beclin 1 evolutionarily conserved domain(ECD)

4ddp, resolution 1.55Å

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