2h5x: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2h5x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H5X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H5X FirstGlance]. <br> | <table><tr><td colspan='2'>[[2h5x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H5X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2H5X FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ruvA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ruvA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h5x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h5x RCSB], [http://www.ebi.ac.uk/pdbsum/2h5x PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2h5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h5x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2h5x RCSB], [http://www.ebi.ac.uk/pdbsum/2h5x PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/RUVA_MYCTU RUVA_MYCTU]] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Alipio, E Z | [[Category: Alipio, E Z]] | ||
[[Category: Bursey, E | [[Category: Bursey, E]] | ||
[[Category: Chandra, N R | [[Category: Chandra, N R]] | ||
[[Category: Hung, L W | [[Category: Hung, L W]] | ||
[[Category: Khanduja, J S | [[Category: Khanduja, J S]] | ||
[[Category: Kim, C Y | [[Category: Kim, C Y]] | ||
[[Category: Lekin, T | [[Category: Lekin, T]] | ||
[[Category: Muniyappa, K | [[Category: Muniyappa, K]] | ||
[[Category: Prabu, J R | [[Category: Prabu, J R]] | ||
[[Category: Segelke, B | [[Category: Segelke, B]] | ||
[[Category: Terwilliger, T C | [[Category: Terwilliger, T C]] | ||
[[Category: Thamotharan, S | [[Category: Thamotharan, S]] | ||
[[Category: Toppani, D | [[Category: Toppani, D]] | ||
[[Category: Vijayan, M | [[Category: Vijayan, M]] | ||
[[Category: Waldo, G S | [[Category: Waldo, G S]] | ||
[[Category: Yu, M | [[Category: Yu, M]] | ||
[[Category: Dna binding protein]] | [[Category: Dna binding protein]] | ||
[[Category: Holliday junction binding]] | [[Category: Holliday junction binding]] | ||
[[Category: Recombination]] | [[Category: Recombination]] | ||
[[Category: Ruva]] | [[Category: Ruva]] | ||
Revision as of 17:36, 25 December 2014
RuvA from Mycobacterium tuberculosis
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