2erz: Difference between revisions

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[[Image:2erz.gif|left|200px]]<br /><applet load="2erz" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2erz.gif|left|200px]]
caption="2erz, resolution 2.200&Aring;" />
 
'''Crystal Structure of c-AMP Dependent Kinase (PKA) bound to hydroxyfasudil'''<br />
{{Structure
|PDB= 2erz |SIZE=350|CAPTION= <scene name='initialview01'>2erz</scene>, resolution 2.200&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=HFS:1-(1-HYDROXY-5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE'>HFS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE= Prkaca, Pkaca ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
}}
 
'''Crystal Structure of c-AMP Dependent Kinase (PKA) bound to hydroxyfasudil'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2ERZ is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=HFS:'>HFS</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ERZ OCA].  
2ERZ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ERZ OCA].  


==Reference==
==Reference==
The structure of dimeric ROCK I reveals the mechanism for ligand selectivity., Jacobs M, Hayakawa K, Swenson L, Bellon S, Fleming M, Taslimi P, Doran J, J Biol Chem. 2006 Jan 6;281(1):260-8. Epub 2005 Oct 24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16249185 16249185]
The structure of dimeric ROCK I reveals the mechanism for ligand selectivity., Jacobs M, Hayakawa K, Swenson L, Bellon S, Fleming M, Taslimi P, Doran J, J Biol Chem. 2006 Jan 6;281(1):260-8. Epub 2005 Oct 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16249185 16249185]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: fasudil kinase]]
[[Category: fasudil kinase]]


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