2esd: Difference between revisions

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[[Image:2esd.gif|left|200px]]<br /><applet load="2esd" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2esd.gif|left|200px]]
caption="2esd, resolution 2.55&Aring;" />
 
'''Crystal Structure of thioacylenzyme intermediate of an Nadp Dependent Aldehyde Dehydrogenase'''<br />
{{Structure
|PDB= 2esd |SIZE=350|CAPTION= <scene name='initialview01'>2esd</scene>, resolution 2.55&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=G3H:GLYCERALDEHYDE-3-PHOSPHATE'>G3H</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(NADP(+)) Glyceraldehyde-3-phosphate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.9 1.2.1.9]
|GENE=
}}
 
'''Crystal Structure of thioacylenzyme intermediate of an Nadp Dependent Aldehyde Dehydrogenase'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2ESD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans] with <scene name='pdbligand=NAP:'>NAP</scene> and <scene name='pdbligand=G3H:'>G3H</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(NADP(+)) Glyceraldehyde-3-phosphate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.9 1.2.1.9] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ESD OCA].  
2ESD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ESD OCA].  


==Reference==
==Reference==
The first crystal structure of a thioacylenzyme intermediate in the ALDH family: new coenzyme conformation and relevance to catalysis., D'Ambrosio K, Pailot A, Talfournier F, Didierjean C, Benedetti E, Aubry A, Branlant G, Corbier C, Biochemistry. 2006 Mar 7;45(9):2978-86. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16503652 16503652]
The first crystal structure of a thioacylenzyme intermediate in the ALDH family: new coenzyme conformation and relevance to catalysis., D'Ambrosio K, Pailot A, Talfournier F, Didierjean C, Benedetti E, Aubry A, Branlant G, Corbier C, Biochemistry. 2006 Mar 7;45(9):2978-86. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16503652 16503652]
[[Category: Glyceraldehyde-3-phosphate dehydrogenase (NADP(+))]]
[[Category: Glyceraldehyde-3-phosphate dehydrogenase (NADP(+))]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: ternary complex]]
[[Category: ternary complex]]


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