2ev9: Difference between revisions

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[[Image:2ev9.gif|left|200px]]<br /><applet load="2ev9" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ev9.gif|left|200px]]
caption="2ev9, resolution 1.90&Aring;" />
 
'''Crystal Structure of Shikimate 5-Dehydrogenase (AroE) from Thermus Thermophilus HB8 in complex with NADP(H) and shikimate'''<br />
{{Structure
|PDB= 2ev9 |SIZE=350|CAPTION= <scene name='initialview01'>2ev9</scene>, resolution 1.90&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SKM:(3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>SKM</scene> and <scene name='pdbligand=NAP:NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE'>NAP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Shikimate_dehydrogenase Shikimate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.25 1.1.1.25]
|GENE= AroE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])
}}
 
'''Crystal Structure of Shikimate 5-Dehydrogenase (AroE) from Thermus Thermophilus HB8 in complex with NADP(H) and shikimate'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2EV9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=SKM:'>SKM</scene> and <scene name='pdbligand=NAP:'>NAP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Shikimate_dehydrogenase Shikimate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.25 1.1.1.25] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EV9 OCA].  
2EV9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EV9 OCA].  


==Reference==
==Reference==
Crystal structures of shikimate dehydrogenase AroE from Thermus thermophilus HB8 and its cofactor and substrate complexes: insights into the enzymatic mechanism., Bagautdinov B, Kunishima N, J Mol Biol. 2007 Oct 19;373(2):424-38. Epub 2007 Aug 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17825835 17825835]
Crystal structures of shikimate dehydrogenase AroE from Thermus thermophilus HB8 and its cofactor and substrate complexes: insights into the enzymatic mechanism., Bagautdinov B, Kunishima N, J Mol Biol. 2007 Oct 19;373(2):424-38. Epub 2007 Aug 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17825835 17825835]
[[Category: Shikimate dehydrogenase]]
[[Category: Shikimate dehydrogenase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: cofactor]]
[[Category: cofactor]]
[[Category: dimer]]
[[Category: dimer]]
[[Category: national project on protein structural and functional analyses]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: nppsfa]]
[[Category: oxidoreductase]]
[[Category: oxidoreductase]]
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[[Category: rsgi]]
[[Category: rsgi]]
[[Category: shikimate]]
[[Category: shikimate]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: substrate]]
[[Category: substrate]]
[[Category: x-ray diffraction]]
[[Category: x-ray diffraction]]


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