2pku: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2pku]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PKU FirstGlance]. <br>
<table><tr><td colspan='2'>[[2pku]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PKU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2PKU FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pku OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pku RCSB], [http://www.ebi.ac.uk/pdbsum/2pku PDBsum]</span></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2pku FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pku OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2pku RCSB], [http://www.ebi.ac.uk/pdbsum/2pku PDBsum]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PICK1_RAT PICK1_RAT]] Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel.<ref>PMID:16138078</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Pan, L.]]
[[Category: Pan, L]]
[[Category: Shen, C.]]
[[Category: Shen, C]]
[[Category: Shi, Y.]]
[[Category: Shi, Y]]
[[Category: Wu, H.]]
[[Category: Wu, H]]
[[Category: Xia, J.]]
[[Category: Xia, J]]
[[Category: Zhang, M.]]
[[Category: Zhang, M]]
[[Category: Protein binding]]
[[Category: Protein binding]]
[[Category: Protein complex]]
[[Category: Protein complex]]