2ivx: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ivx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IVX FirstGlance]. <br> | <table><tr><td colspan='2'>[[2ivx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IVX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IVX FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ivx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ivx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ivx RCSB], [http://www.ebi.ac.uk/pdbsum/2ivx PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ivx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ivx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ivx RCSB], [http://www.ebi.ac.uk/pdbsum/2ivx PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CCNT2_HUMAN CCNT2_HUMAN]] Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin T) complex, also called positive transcription elongation factor B (P-TEFB), which is proposed to facilitate the transition from abortive to production elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNAP II).<ref>PMID:10364329</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C | [[Category: Arrowsmith, C]] | ||
[[Category: Berridge, G | [[Category: Berridge, G]] | ||
[[Category: Bullock, A N | [[Category: Bullock, A N]] | ||
[[Category: Das, S | [[Category: Das, S]] | ||
[[Category: Debreczeni, J E | [[Category: Debreczeni, J E]] | ||
[[Category: Delft, F Von | [[Category: Delft, F Von]] | ||
[[Category: Edwards, A | [[Category: Edwards, A]] | ||
[[Category: Fedorov, O | [[Category: Fedorov, O]] | ||
[[Category: Gorrec, F | [[Category: Gorrec, F]] | ||
[[Category: Knapp, S | [[Category: Knapp, S]] | ||
[[Category: Papagrigoriou, E | [[Category: Papagrigoriou, E]] | ||
[[Category: Pike, A C.W | [[Category: Pike, A C.W]] | ||
[[Category: Savitsky, P | [[Category: Savitsky, P]] | ||
[[Category: Sundstrom, M | [[Category: Sundstrom, M]] | ||
[[Category: Turnbull, A | [[Category: Turnbull, A]] | ||
[[Category: Ugochukwu, E | [[Category: Ugochukwu, E]] | ||
[[Category: Weigelt, J | [[Category: Weigelt, J]] | ||
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Cell division]] | [[Category: Cell division]] | ||