2f2k: Difference between revisions

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[[Image:2f2k.gif|left|200px]]~~<br /><applet load~~="2f2k~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:2f2k.gif|left|200px]]

~~caption="~~2f2k, resolution 1.94Å" />

'''Aldose reductase tertiary complex with NADPH and DEG'''~~<br />~~

{{Structure

|PDB= 2f2k |SIZE=350|CAPTION= <scene name='initialview01'>2f2k</scene>, resolution 1.94Å

|SITE=

|LIGAND= <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene> and <scene name='pdbligand=TGG:GAMMA-GLUTAMYL-S-(1,2-DICARBOXYETHYL)CYSTEINYLGLYCINE'>TGG</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21]

|GENE= AKR1B1, ALDR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])

}}

'''Aldose reductase tertiary complex with NADPH and DEG'''

==Overview==

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==About this Structure==

2F2K is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens~~] with <scene name='pdbligand=NDP:'>NDP</scene> and <scene name='pdbligand=TGG:'>TGG</scene> as [http://en.wikipedia.org/wiki/ligands ligands~~]. ~~Active as [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21]~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2K OCA].

2F2K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2K OCA].

==Reference==

Structure of a glutathione conjugate bound to the active site of aldose reductase., Singh R, White MA, Ramana KV, Petrash JM, Watowich SJ, Bhatnagar A, Srivastava SK, Proteins. 2006 Jul 1;64(1):101-10. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~16639747 16639747]

Structure of a glutathione conjugate bound to the active site of aldose reductase., Singh R, White MA, Ramana KV, Petrash JM, Watowich SJ, Bhatnagar A, Srivastava SK, Proteins. 2006 Jul 1;64(1):101-10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16639747 16639747]

[[Category: Aldehyde reductase]]

[[Category: Homo sapiens]]

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[[Category: tertiary complex]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:47:18 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2f2k.gif|left|200px]]<br /><applet load="2f2k" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2f2k.gif|left|200px]]
-caption="2f2k, resolution 1.94&Aring;" />
-'''Aldose reductase tertiary complex with NADPH and DEG'''<br />
+ {{Structure
+|PDB= 2f2k |SIZE=350|CAPTION= <scene name='initialview01'>2f2k</scene>, resolution 1.94&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene> and <scene name='pdbligand=TGG:GAMMA-GLUTAMYL-S-(1,2-DICARBOXYETHYL)CYSTEINYLGLYCINE'>TGG</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21]
+|GENE= AKR1B1, ALDR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''Aldose reductase tertiary complex with NADPH and DEG'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-F2K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NDP:'>NDP</scene> and <scene name='pdbligand=TGG:'>TGG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2K OCA].
+F2K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F2K OCA].
 ==Reference==
-Structure of a glutathione conjugate bound to the active site of aldose reductase., Singh R, White MA, Ramana KV, Petrash JM, Watowich SJ, Bhatnagar A, Srivastava SK, Proteins. 2006 Jul 1;64(1):101-10. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16639747 16639747]
+Structure of a glutathione conjugate bound to the active site of aldose reductase., Singh R, White MA, Ramana KV, Petrash JM, Watowich SJ, Bhatnagar A, Srivastava SK, Proteins. 2006 Jul 1;64(1):101-10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16639747 16639747]
 [[Category: Aldehyde reductase]]
 [[Category: Homo sapiens]]
@@ Line 28: / Line 37: @@
 [[Category: tertiary complex]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:17:07 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:47:18 2008''