4e46: Difference between revisions
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==Structure of Rhodococcus rhodochrous haloalkane dehalogenase DhaA in complex with 2-propanol== | |||
<StructureSection load='4e46' size='340' side='right' caption='[[4e46]], [[Resolution|resolution]] 1.26Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4e46]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_rhodochrous Rhodococcus rhodochrous]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E46 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4E46 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fbw|3fbw]], [[3fwh|3fwh]], [[3g9x|3g9x]], [[1bn6|1bn6]], [[1cqw|1cqw]]</td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dhaA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1829 Rhodococcus rhodochrous])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Haloalkane_dehalogenase Haloalkane dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.5 3.8.1.5] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4e46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e46 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4e46 RCSB], [http://www.ebi.ac.uk/pdbsum/4e46 PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH]] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane. | |||
== | ==See Also== | ||
[[ | *[[Dehalogenase|Dehalogenase]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Haloalkane dehalogenase]] | [[Category: Haloalkane dehalogenase]] | ||
[[Category: Rhodococcus rhodochrous]] | [[Category: Rhodococcus rhodochrous]] | ||
[[Category: Chaloupkova, R | [[Category: Chaloupkova, R]] | ||
[[Category: Damborsky, J | [[Category: Damborsky, J]] | ||
[[Category: Smatanova, I Kuta | [[Category: Smatanova, I Kuta]] | ||
[[Category: Stsiapanava, A | [[Category: Stsiapanava, A]] | ||
[[Category: Alpha/beta hydrolase fold]] | [[Category: Alpha/beta hydrolase fold]] | ||
[[Category: Catalytic pentad]] | [[Category: Catalytic pentad]] | ||
