3mn9: Difference between revisions

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mn9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mn9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mn9 RCSB], [http://www.ebi.ac.uk/pdbsum/3mn9 PDBsum]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/ACT1_DROME ACT1_DROME]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction. [[http://www.uniprot.org/uniprot/SPIR_DROME SPIR_DROME]] Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Promotes dissociation of capu from the barbed end of actin filaments. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for localization of determinants within the developing oocyte to the posterior pole and to the dorsal anterior corner. Links Rho family signaling and Jnk function to the actin cytoskeleton.<ref>PMID:10556052</ref> <ref>PMID:10744979</ref> <ref>PMID:15674283</ref> <ref>PMID:20538977</ref> <ref>PMID:21730168</ref>

== Publication Abstract from PubMed ==

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 <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mn9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mn9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mn9 RCSB], [http://www.ebi.ac.uk/pdbsum/3mn9 PDBsum]</span></td></tr>
 </table>
+== Function ==
+[[http://www.uniprot.org/uniprot/ACT1_DROME ACT1_DROME]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction. [[http://www.uniprot.org/uniprot/SPIR_DROME SPIR_DROME]] Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Promotes dissociation of capu from the barbed end of actin filaments. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for localization of determinants within the developing oocyte to the posterior pole and to the dorsal anterior corner. Links Rho family signaling and Jnk function to the actin cytoskeleton.<ref>PMID:10556052</ref> <ref>PMID:10744979</ref> <ref>PMID:15674283</ref> <ref>PMID:20538977</ref> <ref>PMID:21730168</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==