2f6f: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 1: Line 1:
[[Image:2f6f.gif|left|200px]]<br /><applet load="2f6f" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2f6f.gif|left|200px]]
caption="2f6f, resolution 2.0&Aring;" />
 
'''The structure of the S295F mutant of human PTP1B'''<br />
{{Structure
|PDB= 2f6f |SIZE=350|CAPTION= <scene name='initialview01'>2f6f</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=MG:MAGNESIUM ION'>MG</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48]
|GENE= PTPN1, PTP1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''The structure of the S295F mutant of human PTP1B'''
 


==Overview==
==Overview==
Line 10: Line 19:


==About this Structure==
==About this Structure==
2F6F is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F6F OCA].  
2F6F is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F6F OCA].  


==Reference==
==Reference==
Residues distant from the active site influence protein-tyrosine phosphatase 1B inhibitor binding., Montalibet J, Skorey K, McKay D, Scapin G, Asante-Appiah E, Kennedy BP, J Biol Chem. 2006 Feb 24;281(8):5258-66. Epub 2005 Dec 6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16332678 16332678]
Residues distant from the active site influence protein-tyrosine phosphatase 1B inhibitor binding., Montalibet J, Skorey K, McKay D, Scapin G, Asante-Appiah E, Kennedy BP, J Biol Chem. 2006 Feb 24;281(8):5258-66. Epub 2005 Dec 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16332678 16332678]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
Line 26: Line 35:
[[Category: MG]]
[[Category: MG]]
[[Category: ligand binding]]
[[Category: ligand binding]]
[[Category: mutations]]
[[Category: mutation]]
[[Category: phosphatase]]
[[Category: phosphatase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:18:12 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:48:39 2008''
Retrieved from "https://proteopedia.org/2f6f"