4i3q: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i3q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i3q RCSB], [http://www.ebi.ac.uk/pdbsum/4i3q PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4i3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i3q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4i3q RCSB], [http://www.ebi.ac.uk/pdbsum/4i3q PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CP3A4_HUMAN CP3A4_HUMAN]] Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide.<ref>PMID:11159812</ref> | |||
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== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
