4qmg: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qmg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qmg RCSB], [http://www.ebi.ac.uk/pdbsum/4qmg PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qmg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qmg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qmg RCSB], [http://www.ebi.ac.uk/pdbsum/4qmg PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/SND1_HUMAN SND1_HUMAN]] Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).<ref>PMID:7651391</ref> [[http://www.uniprot.org/uniprot/LYRIC_HUMAN LYRIC_HUMAN]] Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.<ref>PMID:15927426</ref> <ref>PMID:16452207</ref> <ref>PMID:18316612</ref> <ref>PMID:19111877</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Guo, F | [[Category: Guo, F]] | ||
[[Category: Kang, Y | [[Category: Kang, Y]] | ||
[[Category: Satyshur, K | [[Category: Satyshur, K]] | ||
[[Category: Stanevich, V | [[Category: Stanevich, V]] | ||
[[Category: Wan, L | [[Category: Wan, L]] | ||
[[Category: Xing, Y | [[Category: Xing, Y]] | ||
[[Category: Breast cancer]] | [[Category: Breast cancer]] | ||
[[Category: Dna/rna-binding]] | [[Category: Dna/rna-binding]] | ||
