1m2c: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1m2c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Conus_magus Conus magus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M2C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M2C FirstGlance]. <br> | <table><tr><td colspan='2'>[[1m2c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Conus_magus Conus magus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M2C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M2C FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m2c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m2c RCSB], [http://www.ebi.ac.uk/pdbsum/1m2c PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m2c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1m2c RCSB], [http://www.ebi.ac.uk/pdbsum/1m2c PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CXA2_CONMA CXA2_CONMA]] Alpha-conotoxins bind to the nicotinic acetylcholine receptors (nAChR) and inhibit them. This toxin blocks neuronal mammalian nAChRs (alpha-6 or -3/beta-2 or -3 > alpha-3/beta-2 > alpha-3/beta-4 = alpha-4/beta-2).<ref>PMID:8631783</ref> <ref>PMID:11044728</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 19: | Line 21: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Conus magus]] | [[Category: Conus magus]] | ||
[[Category: Koerber, S C | [[Category: Koerber, S C]] | ||
[[Category: Mcintosh, J M | [[Category: Mcintosh, J M]] | ||
[[Category: Olivera, B M | [[Category: Olivera, B M]] | ||
[[Category: Rivier, J E | [[Category: Rivier, J E]] | ||
[[Category: Shon, K J | [[Category: Shon, K J]] | ||
[[Category: Cholinergic modulation]] | [[Category: Cholinergic modulation]] | ||
[[Category: Dopamine release]] | [[Category: Dopamine release]] | ||
