2fjx: Difference between revisions

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[[Image:2fjx.gif|left|200px]]<br /><applet load="2fjx" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fjx.gif|left|200px]]
caption="2fjx, resolution 1.8&Aring;" />
 
'''RT29 bound to D(CTTGAATGCATTCAAG) in complex with MMLV RT catalytic fragment'''<br />
{{Structure
|PDB= 2fjx |SIZE=350|CAPTION= <scene name='initialview01'>2fjx</scene>, resolution 1.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=HXL:2-(4-(4-CARBAMIMIDOYLPHENOXY)PHENYL)-1H-BENZO[D]IMIDAZOLE-6-CARBOXIMIDAMIDE'>HXL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49]
|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11801 Moloney murine leukemia virus])
}}
 
'''RT29 bound to D(CTTGAATGCATTCAAG) in complex with MMLV RT catalytic fragment'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FJX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Moloney_murine_leukemia_virus Moloney murine leukemia virus] with <scene name='pdbligand=HXL:'>HXL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FJX OCA].  
2FJX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Moloney_murine_leukemia_virus Moloney murine leukemia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FJX OCA].  


==Reference==
==Reference==
A high-throughput, high-resolution strategy for the study of site-selective DNA binding agents: analysis of a "highly twisted" benzimidazole-diamidine., Goodwin KD, Lewis MA, Tanious FA, Tidwell RR, Wilson WD, Georgiadis MM, Long EC, J Am Chem Soc. 2006 Jun 21;128(24):7846-54. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16771498 16771498]
A high-throughput, high-resolution strategy for the study of site-selective DNA binding agents: analysis of a "highly twisted" benzimidazole-diamidine., Goodwin KD, Lewis MA, Tanious FA, Tidwell RR, Wilson WD, Georgiadis MM, Long EC, J Am Chem Soc. 2006 Jun 21;128(24):7846-54. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16771498 16771498]
[[Category: Moloney murine leukemia virus]]
[[Category: Moloney murine leukemia virus]]
[[Category: RNA-directed DNA polymerase]]
[[Category: RNA-directed DNA polymerase]]
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[[Category: water-mediated interaction]]
[[Category: water-mediated interaction]]


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