3bm9: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3bm9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BM9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BM9 FirstGlance]. <br> | <table><tr><td colspan='2'>[[3bm9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BM9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BM9 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BXZ:4-BROMO-6-(6-HYDROXY-1,2-BENZISOXAZOL-3-YL)BENZENE-1,3-DIOL'>BXZ</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BXZ:4-BROMO-6-(6-HYDROXY-1,2-BENZISOXAZOL-3-YL)BENZENE-1,3-DIOL'>BXZ</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bmy|3bmy]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3bmy|3bmy]]</td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HSP90AA1, HSP90A, HSPC1, HSPCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HSP90AA1, HSP90A, HSPC1, HSPCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bm9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bm9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bm9 RCSB], [http://www.ebi.ac.uk/pdbsum/3bm9 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3bm9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bm9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3bm9 RCSB], [http://www.ebi.ac.uk/pdbsum/3bm9 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arndt, K | [[Category: Arndt, K]] | ||
[[Category: Boschelli, F | [[Category: Boschelli, F]] | ||
[[Category: Chopra, R | [[Category: Chopra, R]] | ||
[[Category: Ellingboe, J | [[Category: Ellingboe, J]] | ||
[[Category: Golas, J | [[Category: Golas, J]] | ||
[[Category: Gopalsamy, A | [[Category: Gopalsamy, A]] | ||
[[Category: Jacob, J | [[Category: Jacob, J]] | ||
[[Category: Johnson, J | [[Category: Johnson, J]] | ||
[[Category: Lee, F | [[Category: Lee, F]] | ||
[[Category: Nilakantan, R | [[Category: Nilakantan, R]] | ||
[[Category: Peterson, R | [[Category: Peterson, R]] | ||
[[Category: Shi, M | [[Category: Shi, M]] | ||
[[Category: Svenson, K | [[Category: Svenson, K]] | ||
[[Category: Tam, M S | [[Category: Tam, M S]] | ||
[[Category: Vogan, E M | [[Category: Vogan, E M]] | ||
[[Category: Wen, Y | [[Category: Wen, Y]] | ||
[[Category: Atp binding domain]] | [[Category: Atp binding domain]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
