2fqt: Difference between revisions

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[[Image:2fqt.gif|left|200px]]<br /><applet load="2fqt" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fqt.gif|left|200px]]
caption="2fqt, resolution 1.79&Aring;" />
 
'''Crystal structure of B.subtilis LuxS in complex with (2S)-2-Amino-4-[(2R,3S)-2,3-dihydroxy-3-N-hydroxycarbamoyl-propylmercapto]butyric acid'''<br />
{{Structure
|PDB= 2fqt |SIZE=350|CAPTION= <scene name='initialview01'>2fqt</scene>, resolution 1.79&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene> and <scene name='pdbligand=H1D:(2S)-2-AMINO-4-[(2R,3S)-2,3-DIHYDROXY-3-N-HYDROXYCARBAMOYL-PROPYLMERCAPTO]BUTYRIC ACID'>H1D</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/S-ribosylhomocysteine_lyase S-ribosylhomocysteine lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.21 4.4.1.21]
|GENE= luxS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])
}}
 
'''Crystal structure of B.subtilis LuxS in complex with (2S)-2-Amino-4-[(2R,3S)-2,3-dihydroxy-3-N-hydroxycarbamoyl-propylmercapto]butyric acid'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FQT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=CO:'>CO</scene> and <scene name='pdbligand=H1D:'>H1D</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/S-ribosylhomocysteine_lyase S-ribosylhomocysteine lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.21 4.4.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQT OCA].  
2FQT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FQT OCA].  


==Reference==
==Reference==
Design and synthesis of substrate and intermediate analogue inhibitors of S-ribosylhomocysteinase., Shen G, Rajan R, Zhu J, Bell CE, Pei D, J Med Chem. 2006 May 18;49(10):3003-11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16686542 16686542]
Design and synthesis of substrate and intermediate analogue inhibitors of S-ribosylhomocysteinase., Shen G, Rajan R, Zhu J, Bell CE, Pei D, J Med Chem. 2006 May 18;49(10):3003-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16686542 16686542]
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: S-ribosylhomocysteine lyase]]
[[Category: S-ribosylhomocysteine lyase]]
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[[Category: H1D]]
[[Category: H1D]]
[[Category: SO4]]
[[Category: SO4]]
[[Category: luxs]]
[[Category: lux]]
[[Category: quorum sensing]]
[[Category: quorum sensing]]


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